Carter, Lee, Sanford’s ICC 2018 Adam and Eve paper, Congratulations Bill Basener

Bill Basener (a participant here) co-authored a paper with John Sanford. He was given the honor of delivering a KEYNOTE ADDRESS at an international SECULAR biology conference. A video of his presentation is available in a link inside my write up of his presentation below. He alluded to some of the helpful input from his critics at TheSkepticalZone in his talk:

John Sanford is sort of the “Papa John” of creationist genetics. It is customary for the leader of a research group to be listed as the last author in a publication. That convention is seen in a variety of papers and books such as Rupe & Sanford; Basener & Sanford; Carter, Lee & Sanford; Montanyez, Fernandez, Marks & Sanford; and let’s not forget the Legendary High Velocity Team of Klein, Wolf, Wu & Sanford that permanently ensured the infusion of intelligently designed genes into a sizable fraction of Genetically Modified Organisms on planet Earth.

And perhaps one day in the distant future there will be a paper, “Cordova & Sanford”! 🙂

Below is a link of a paper from Papa John’s team about Adam and Eve which will be presented this week, July 29,2018 – August 1, 2018 at the 8th International Conference on Creationism

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ICC 2018, mtDNA hetero and homoplasmy

In the link below are the abstracts with links to the papers presented at the International Conference on Creationism 2018 in Pittsburgh, PA July 29-August 1, 2018. Those presenting are professors at Christian colleges, professors already expelled from secular colleges, or professors at secular colleges who (by God’s grace) can’t be expelled. 🙂

A topic I will raise among the population geneticists there (John C. Sanford, Rob Carter, Nathaniel Jeanson, and others) is the issue of heteroplasmy in mtDNA as they are presenting on these topics.

Mature human cells have 100,000 to 600,000 mitochondrion. So how can a cell be mostly homoplasmic yet have mtDNA mutations that are reflected in lineages whereby an individual has a mostly homoplasmic mtDNA that enable us to identify the 7 daughters of Eve (to quote Oxford Geneticist Bryan Sykes).
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Does embryo development process require ID?

Jonathan Wells, who is an embryologist and an ID advocate, has a very interesting paper and video on the issue of ontogeny (embryo development)  and  the origins of information needed in the process of cell differentiation…

Wells thinks that a major piece of information needed in the process of embryo development can’t be explained by DNA,  and therefore may require an intervention of an outside source of information, such as ID/God…

If you don’t want to watch the whole video, starting at about 40 min mark is just as good but especially at 43 min.

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The Death Evolution

Death has been on everyone’s mind at one time or another… It’s unavoidable…
Some are fascinated by death; mainly  the possibility of better afterlife. Some, or the great majority of people, are frightened by it. It seems the unknown of after-death is one of the main factors causing many to tremble…

However, it turns out that Craig Venter, the pioneer of  the human genome project and the supposed creator of artificial life, turned his attention and efforts toward decoding death… here

It seems obvious Venter believes that death is be caused by genetics; some genetic mutations that could be fixed and we could live forever, otherwise he wouldn’t be digging in the genome looking to fix the death code…

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2. Earth is the Center of the Universe? Full Movie

This is a follow up to Earth is the Center of the Universe? OP with the link to the full documentary entitled The Principle. It is really worth to watch it in its entirety just to get the sense of how cosmologist, like Lawrence Krauss, and many other scientists deliberately resist the data  (verified by 3 different probes) that Axis of Evil are pointing to the special location of the Earth in the Universe…

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Felsenstein presents the 37th Fisher Memorial Lecture

Joe Felsenstein, who posts and comments in The Skeptical Zone, presented the 37th Fisher Memorial Lecture on January 4, 2018. The video recording of his lecture is now available. I’d say that the cover frame, at the very least, was well worth the wait.

Rooting out confusion is much harder than sowing it

Excuse me for attaching to this post a brief rejoinder to a pathetic response to the lecture. Andrew Jones’s “The Law of Zero Magic” appeared in the flagship publication of the intelligent design (ID) movement, Evolution News & Science Today. The title is hugely ironic, inasmuch as the movement conceives of intelligent design as violation of a law of nature, and struggles to devise the law that is violated. Continue reading

Rejoinder to Basener and Sanford’s reply, part I

William Basener and John Sanford have responded here to my post concerning whether R.A. Fisher’s Fundamental Theorem of Natural Selection is critical to work on the theoretical population genetics of the interaction between mutation and natural selection. (This reply by Basener and Sanford is also reposted here.) Continue reading

What is the evidence for “purposeful intervention”?

FMM: Purposeful intervention is pretty much the opposite of random mutation.

FMM notes in the same comment:

 If there in nothing about an idea that distinguishes it from it’s alternative it seems to be superfluous.

So the idea is “non designed mutations” and the alternative is “purposeful intervention”.

Give that, and given FMM has not discarded the idea of purposeful intervention there must be something that distinguishes it from non designed mutations.

What is that distinguishing factor? What is the actual evidence for “purposeful intervention” regarding mutations?

And, more broadly, what is the evidence for “purposeful intervention” in any area of biology? Apart from, of course, wishful thinking.

1. Evolution or Design? Duons

Have you ever tried writing palindromes? How about writing phrases that can be read the same way in either direction? Here are some examples:
A man, a plan, a canal: Panama
Live not on evil
Was it a car or a cat I saw
These sentences were no doubt designed…
Can you imagine writing a book that can be read forwards and backwards containing 2 different stories that made sense? Not an easy task…

Watch the video and pay special attention to the following examples:

  1. Alternative splicing of RNA that produces multiple proteins from one gene
  2. Duons – Overlapping sequences that code for both protein expression and transcription factor binding sites simultaneously
  3. Dual coding genes in which one sequence is read in multiple frames to produce completely different protein

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1. What is life? The Definition

As some of you already know, or suspect, I have decided to “return” to publishing OPs at TSZ. There are many reasons for that but mainly to save TSZ from what many blogs like this one suffered; the inevitable death. So, let’s see and hope that my take on old ideas can help to revitalize TSZ again… I have new ideas too… Continue reading

Does all of evolutionary theory rest on Fisher’s Fundamental Theorem?

The blogs of creationists and ID advocates have been buzzing with the news that a new paper by William Basener and John Sanford, in Journal of Mathematical Biology, shows that natural selection will not lead to the increase of fitness. Some of the blog reports will be found here, here, here, here, here, and here. Sal Cordova has been quoting the paper at length in a comment here.

Basener and Sanford argue that the Fundamental Theorem of Natural Selection, put forward by R.A. Fisher in his book The Genetical Theory of Natural Selection in 1930, was the main foundation of the Modern Evolutionary Synthesis of the 1930s and 1940s. And that when mutation is added to the evolutionary forces modeled by that theorem, it can be shown that fitnesses typically decline rather than increase. They argue that Fisher expected increase of fitness to be typical (they call this Fisher’s Theorem”).

I’m going to argue here that this is a wrong reading of the history of theoretical population genetics and of the history of the Modern Synthesis. In a separate post, in a few days at Panda’s Thumb, I will argue that Basener and Sanford’s computer simulation has a fatal flaw that makes its behavior quite atypical of evolutionary processes.

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Purpose and Desire

Purpose and Desire: What Makes Something “Alive” and Why Modern Darwinism Has Failed to Explain It is the new book by physiologist J. Scott Turner, author of The Tinkerer’s Accomplice: How Design Emerges from Life Itself.

The book may make some “skeptics” uncomfortable, but maybe they should read it anyways.

From the book:

I have come to believe that there is something presently wrong with how we scientists think about life, its existence, its origins, and its evolution.

Without a coherent theory of life, whatever we think about life doesn’t hold water. This applies to the major contribution we claim that the modern science of life offers to the popular culture: Darwinism.

… there sits at the heart of modern Darwinism an unresolved tautology that undermines its validity.

… do we have a coherent theory of evolution? The firmly settled answer to this question is supposed to be “yes” …

I intend to argue in this book that the answer to my question might actually be “no.”

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The Mystery of Evolution: One Down

My kids just informed me that they have seen an okapi evolving, or transitioning into a zebra

Okapi’s stripes appear to be no doubt the same as zebra’s…

Zebra, Equus quagga, Masai Mara Reserve, Kenya : Stock Photo

Well, at least we have one example of species transitioning into another…out of 10 billion and this one looks like a stunner….

I have to run!

I’ll fill in the rest when I get back…


It turns out that okapi is considered to be more closely related to giraffe than to zebra…if at all…That is surprising…because okapi and zebra do look alike just okapi is missing some stripes…No wonder my kids fell for it…as did some experts…

“…The okapi and the giraffe were assigned to the same order (Artiodactyla) because they both have cloven hooves, and to the same family (Giraffidae) because they share certain distinctive features: Both have large eyes and ears, thin lips and a long, extensible tongue that allows them to lick their entire face (even the ears); their backs slope upward from rump to withers; they also share the same dental formula: ( i 0/3, c 0/1, pm 3/3, m 3/3) Ă— 3 = 32. Both, unlike any other mammal, have molars with rugose enamel and bony horns that remain covered with skin throughout life (Nowak 1999, vol. 2, p. 1085).

Yet the rump and legs of an okapi are covered with black-and-white stripes exactly like those of a zebra. Perhaps, then, if okapis had solid hooves instead of cloven ones, they would be classified as perissodactyls (Order Perissodactyla) and would be considered more closely related to zebras than to giraffes. An okapi is about the same size as a Burchell’s zebra.

The chromosome count of an okapi is also like that of a zebra, to which it is not supposed to be related, and unlike that of a giraffe. Giraffes have 30 chromosomes (Taylor et al. 1967; Hösli and Lang 1970; Koulisher et al. 1971), whereas okapis have a variable chromosome number of 44-46, depending on the animal in question; most seem to have 2n = 45 (Ulbrich and Schmitt 1969; Hösli and Lang 1970; Koulisher 1978). The chromosome number of Grevy’s zebra is 2n = 46 and plains zebras have 2n = 44 (Benirschke and Malouf 1967). Variation in chromosome count is itself unusual among mammals, but common in hybrids…”

The 14-16 chromosome difference between giraffe and okapi is striking isn’t it?

Improbable Destinies

Improbable Destinies: Fate, Chance, and the Future of Evolution

I love books like this. Pure wonder about the living world. The beauty. The mystery. Shattering the myths of Darwinism while still clinging desperately to them.

We learn that Darwinism has retarded evolutionary thought for at least a century because the picture that Darwin gave us (which his disciples followed for over a hundred years) was false. Evolution can be tested. It can be observed within human lifetimes. It doesn’t require the infinitesimal insensible aggregations over millenia previously thought. Evolution can be really really fast. Which ought to be good news for young earth creationists.

We also learn that the oft-heard claim that degree of similarity implies degree of relatedness is false. That some species A looks very much like some species B doesn’t at all mean that they are more closely related than some other species which is visibly different.

Another nail in the coffin.

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The Mysteries of Evolution: 6. Endosymbiosis-The second miracle of life after the origin of life

This is one of the most fundamental mysteries of evolution and the origins of multicellular life often called endosymbiosis, which is supposed to explain the origin of eukaryotic cell.

It doesn’t!  Here is why…

What I found perplexing, or even disturbing, is that although it is presented as scientific fact of evolution, as evolution itself often is, there is absolutely not one fact to support that endosybiosis happened or could have happened…

And this the fact…

How could that be?

First of all, the difference between prokaryotic and eukaryotic cell is so staggering that even proposing such quantum leap in evolutionary change goes beyond macroevolutionary claim…

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Invited responses to my nylonase research and the question of “New Proteins Without God’s Help”

Susumo Ohno (who coined the term “junkDNA”) published a paper in 1984 through the National Academy of Sciences that was used by the NCSE, Ken Miller and Dennis Venema to claim “proteins can evolve without God’s help”. At the request of John Sanford, a courtesy associate research professor at Cornell, I was recruited to write a paper to refute Ohno’s evolutionary hypothesis on nylonases. I wrote it under John’s guidance based on his intuitions about genetics, his life-long specialty of 40 years and for which he became famous as attested by the fact he is one of the few geneticists who had their work featured in the Smithsonian National Museum of American History.

The actual paper is now in review, but it is not intended to be published in any journal, but will be released in a variety of channels shortly. It is hoped the material can be used by others to actually create papers that enter peer review. The motivation for releasing the paper in this way is to counter Venema’s book while it is still hot off the press.
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The embarrassing “science” of the origins of life: The missing piece of evidence that persuaded scientists to believe in abiogenesis

What comes to your mind when you hear or read the word science? To most the word science correlates with fact, proof or  even truth.

In my countless debates over the years with scientist and supporters of the origins of life (OOL) or evolution, I’ve often asked the question what convinced them so strongly about something, like abiogenesis. The answers I often got would be:

“…I believe it,  because I believe in science…”

Is it really science? 

No doubt to many, whether scientists or not, the word science is often paralleled with trustworthiness, credibility, reliability, soundness and even authority and influence.

”If something is dubbed as “science”, you’d better believe!” – many would say.

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