Evodoku?

Hi everyone. I think we’re collectively at our best when we explore new things. As things seem we’re a little fractious right now let me offer up my idea for what might be a pleasant diversion.

Sodoku: http://www.sudoku.com/

It kind of has a genome and fitness criteria, right?

 

Let’s take just one 3×3 grid. It could have a genome of 9 digits, and competing fitness functions: (sum or product, max or min) for 3 rows, 3 columns, 2 diagonals and of course some rule about using all the digits (or not if we want better mutations). Each of the 9 genes would affect 2 or 3 (or 4 for gene number 5, in the middle of the square) of the fitness functions. Can we create a simulation, with drifting fitness functions and see how organisms evolve. Will this show islands of function and a path to traverse between them?  This might be fun because a mutation can help in one regard whilst hurting in another. I’ll leave this here for now, let me know if anyone is interested…

 

 

Why David Madison’s Slam Dunk Isn’t One

David Madison is a minister-turned-atheist, who has a PhD in Biblical Studies from Boston University. Madison was raised a liberal Protestant, but he gradually lost his faith while serving as the pastor of two Methodist parishes in Massachusetts. He went on to pursue a business career, but he’s recently written a book titled, Ten Tough Problems in Christian Thought and Belief: A Minister-Turned-Atheist Shows Why You Should Ditch the Faith (see here for one critic’s review and here for a more favorable review).

However, what put me off Madison’s book is what he’s written on his own Web page. His recommended reading list of 200 books, put together for people who want to “find out how Jesus, Christianity and theism have all been so convincingly slam dunked,” includes dozens of books by authors defending the kooky view that Jesus never even existed (a view not shared by any reputable historian – and no, Dr. Richard Carrier doesn’t count as one; nor does Dr. Robert Price, who got trounced when he debated Dr. Bart Ehrman last year on the historicity of Jesus, as Carrier himself admits), and only a handful of books addressing the traditional philosophical arguments for the existence of God, of which Raymond Bradley’s God’s Gravediggers: Why No Deity Exists (Ockham Publishing, 2016) and Michael Martin’s The Cambridge Companion to Atheism appear to be the most substantive. (There are other books attacking Intelligent Design on Madison’s list, but these are beside the point, as ID proponents don’t maintain that their arguments, taken by themselves, prove the existence of any Deity.) And believe it or not, H. L. Mencken, whose credibility on religious and moral issues I have demolished here, here, here and here, makes the list, too. Richard Dawkins’ The God Delusion is on the list (has Madison ever read John Lennox’s response, I wonder?), as well as Bertrand Russell’s Why I Am Not a Christian, which has been refuted ably by David Snoke.

For the benefit of his readers, Madison has also kindly provided chapter summaries for his book, which (I am sorry to say) do not inspire confidence. A few excerpts:

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War in the womb

I’ve never met an IDer or creationist who could explain this, and it should give pause to theistic evolutionists as well.

An article in Aeon:

War in the womb

A ferocious biological struggle between mother and baby belies any sentimental ideas we might have about pregnancy

Suzanne Sadedin is an evolutionary biologist who has worked at Monash University, University of Tennessee, Harvard University, and KU Leuven.

Evolution and Functional Information

Here, one of my brilliant MD PhD students and I study one of the “information” arguments against evolution. What do you think of our study?

I recently put this preprint in biorxiv. To be clear, this study is not yet peer-reviewed, and I do not want anyone to miss this point. This is an “experiment” too. I’m curious to see if these types of studies are publishable. If they are, you might see more from me. Currently it is under review at a very good journal. So it might actually turn the corner and get out there. An a parallel question: do you think this type of work should be published?

 

I’m curious what the community thinks. I hope it is clear enough for non-experts to follow too. We went to great lengths to make the source code for the simulations available in an easy to read and annotated format. My hope is that a college level student could follow the details. And even if you can’t, you can weigh in on if the scientific community should publish this type of work.

Functional Information and Evolution

http://www.biorxiv.org/content/early/2017/03/06/114132

“Functional Information”—estimated from the mutual information of protein sequence alignments—has been proposed as a reliable way of estimating the number of proteins with a specified function and the consequent difficulty of evolving a new function. The fantastic rarity of functional proteins computed by this approach emboldens some to argue that evolution is impossible. Random searches, it seems, would have no hope of finding new functions. Here, we use simulations to demonstrate that sequence alignments are a poor estimate of functional information. The mutual information of sequence alignments fantastically underestimates of the true number of functional proteins. In addition to functional constraints, mutual information is also strongly influenced by a family’s history, mutational bias, and selection. Regardless, even if functional information could be reliably calculated, it tells us nothing about the difficulty of evolving new functions, because it does not estimate the distance between a new function and existing functions. Moreover, the pervasive observation of multifunctional proteins suggests that functions are actually very close to one another and abundant. Multifunctional proteins would be impossible if the FI argument against evolution were true.

Worse than Watergate? Bias in the mainstream media

With the mainstream media mocking what they describe as President Trump’s delusional claim that former President Obama ordered Trump Tower’s phones to be tapped, I thought it would only be fair to invite readers to look at the other side. In a 12-minute video, Mark Levin, a lawyer who was a chief of staff for Attorney General Edwin Meese during the Reagan administration, has laid out what appears to be overwhelming evidence that backs up Trump’s wiretapping claims. Newt Gingrich offers his take here. Matthew Vadum’s article, Obama’s Wiretaps?, in FrontPage magazine, makes for very disturbing reading. Vadum doesn’t pull any punches:

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Sam Harris on objective morality

Since objective morality is The Topic That Won’t Die here at TSZ, I think we need Yet Another Thread to Discuss It.

A Sam Harris quote to get things rolling (h/t walto):

There are two mistakes I see moral subjectivists making. The first mistake is believing in the fact-value dichotomy. The second mistake is conflating moral philosophy and psychology, suggesting that our psychology ought to be the sole determinant of our beliefs.

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WJM throws ID under the bus

I’m really not a fan of doing what I’m about to do.

But anyways, this is WJM @ UD

To be fair, when the proponent of a theory who claims that theory to be scientific fact provides little or nothing in the way of falsifiable predictions and offers largely only sweeping narratives and historical inferences based on ideological assumptions and/or an imagined infinite pool of unqualified possibility, it’s impossible for the opposition to offer specified rebuttals.

Until proponents offer specified, falsifiable predictions, the proper response to such a theory is to “lump everything into a single bucket and dismiss the entire topic.”

Does TSZ suffer from ‘a fundamentally anti-intellectual bias’?

Commenter Kantian Naturalist leveled the following charge against TSZ earlier today:

Folks here would rather persist in their confusion over basic issues than risk the realization that they don’t really understand what they assume they understand.

If you haven’t figured out that there’s a fundamentally anti-intellectual bias to TSZ and there’s really nothing you can do to change it, you’re going to have nothing but frustration in your interactions here.

That is an absurdly sweeping statement. Do some people here persist in their confusions, ignoring opposing arguments? Sure. Do some people express anti-intellectual opinions here? Sure, including KN himself on occasion, amusingly enough. Does this mean that TSZ suffers from “a fundamentally anti-intellectual bias” and that those seeking intelligent discussions are doomed to experience “nothing but frustration” here?

No. KN’s charge is ridiculous and way overblown.

Evo-Info: Publication delayed, supporting materials online

Introduction to Evolutionary Informatics, by Robert J. Marks II, the “Charles Darwin of Intelligent Design”; William A. Dembski, the “Isaac Newton of Information Theory”; and Winston Ewert, the “Charles Ingram of Active Information.” World Scientific, 350 pages. Jan 31 May 1, 2017.
Classification: Engineering mathematics. Engineering analysis. (TA347)
Subjects: Evolutionary computation. Information technology–Mathematics.

I cannot tell you exactly what will be in the forthcoming book by Marks, Dembski, and Ewert. I made it clear in Evo-Info 1 and Evo-Info 2 that I was responding primarily to technical papers on which the book is based. With publication delayed once again, I worry that the authors will revise the manuscript to deflect my criticisms. Thus I’m going to focus for a while on the recent contributions to the “evolutionary informatics” strain of creationism by George D. Montañez, a former advisee of Marks who is presently a doctoral candidate in machine learning at Carnegie Mellon University (advisor: Cosma Shalizi). My advice for George is that if he wants not to taken for a duck, then he had better not walk like a duck and swim like a duck and quack like a duck. Continue reading

Naturalism & the Laws of Nature.

Theoretical physicist Paul Davies wrote:

But what are these ultimate laws and where do they come from? Such questions are often dismissed as being pointless or even unscientific. As the cosmologist Sean Carroll has written, “There is a chain of explanations concerning things that happen in the universe, which ultimately reaches to the fundamental laws of nature and stops… at the end of the day the laws are what they are… And that’s okay. I’m happy to take the universe just as we find it.”

Assuming that Davies is correct, I find it odd that there is little interest for understanding the laws of nature. There are some interesting questions to be answered, such as: Where do the laws come from? How do they cause things to happen? Continue reading

Where is the scientific evidence that arguments change minds?

There is considerable scientific evidence that arguing with people about their beliefs usually has an effect opposite of what you would hope (assuming, generously, that you care more about the effect your arguing has on others than the effect it has on you). I’m sure that most of you have seen reviews of the relevant literature. In any case, I have not the least interest in arguing about the evidence that arguing hardens, rather than changes, beliefs. Why? I insist that, as obviously negative as arguments are, the burden is on the arguer to provide strong evidence that arguing is, on balance, more beneficial than harmful.

It would be entertaining to observe the arguing of the most compulsive of arguers that they actually do not argue. But let’s make that a wee bit harder for them to do, and require that, whatever they regard their not-arguing to be, they present scientific evidence that it generally benefits the people with whom they not-argue. And, no, I have not overlooked the fantasy that the benefit is to the silent Onlookers, and that you are their Champion. Either provide us with evidence that there exists such an effect, or entertain us with your Kairosfocus imitation.

Did Stephen Gould accomplish anything in science. Yes!!

As someone aware of accomplishment in science I note always people are celebrated as having accomplished something but didn’t actually do so.

Its a modern list but therefore I pay attention when folks are celebrated.

I bump into the late Stephen Gould a lot because of evolution/creation conflict.They made a big deal about him and at first glance i thought it was another case of hyping somebody because of a establishment agenda. likewise someone who sold books etc

Yet after reading a major summery of his ion evolution and his punctuated equilibrium contribution I came to a sincere different point of view.

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The Arrival of the Fittest: a book review

Andreas Wagner’s book,The Arrival of the Fittest has been mentioned many times (just try a site search as I’ve just done) since it was published. Petrushka pointed it out in a comment

For anyone interested in whether RMNS can create stuff, I recommend a relatively new book, Arrival of the Fittest. I just bought the Kindle version an haven’t finished, but it has a lot to say about how goldilocks mutations occur.

Much later Mung writes:

Reminds me of petrushka, who is always plugging Andreas Wagner’s Arrival of the Fittest, but will never post an OP on it for discussion.

So I’ve taken the hint and bought the book at last. I can see why people have recommended it. Continue reading

William J. Murray’s alternative facts about Europe

ETA: Unlike “William J. Murray” of The Skeptical Zone, William J. Murray is not on record advocating torture.

There’s much more to the ecosystem of far-right “news” outlets than Breitbart and Infowars. Most of you are aware of that by now. But it seems that few of you are aware of how William J. Murray, the putatively reverend chairman of Religious Freedom Coalition, contributes to the affair. Here he is, in his natural element, showing his true colors (apart from his coif). I didn’t go digging for this video. It comes from the “About” page of Murray’s nonprofit. Here’s a sample:

Europe has been importing hundreds of thousands of Muslims because the women of Europe don’t want to have children. They want to play. They want to have fun. They want to go on long vacations. They want to have money. … They don’t believe that propagation of the species is the most important thing that they’re here for.

You cannot fully grasp the significance this performance without watching the commercial at 20:30.

Republican Senator John McCain chooses his words carefully…

… and yet speaks powerfully to the dangers that we face. This is something that the Europeans in the crowd should not miss (and I don’t know how often they see news of Sunday-morning television in the States). But there’s more than that to my decision to post the video. We presently have a Chrumptian propaganda piece, “Trump Hysteria,” on the front page of The Skeptical Zone. The author, William J. Murray, goes so far in his support of Trump as to endorse torture (see the comments section). John McCain in fact suffered torture as a prisoner in North Vietnam, and has opposed torture steadfastly in his political career. And, perhaps more to the point, he’s anything but hysterical. It is McCain’s caution and restraint that make his remarks chilling.

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Mind blowing presentation by George Church at the NIH

Last week, George Church talked at the school where I take part-time evening classes. I provide a link to that talk. He talked about re-engineered codons (something I’m grateful to Rumraket for introducing me to), stem cell research, human animal chimeras, aging therapies, human genome re-engineering, and just a little bit about ENCODE. Though I have ethical concerns about human/animal chimeras, and human genome re-engineering (like what happens if you mess up), Church goes into the technologies and raises questions as to what our world may look like in the not too distant future. Not that I’m trying to make a point about ID or God by linking this video, but it shows how rapidly we may be forced to deal with certain issues.

I personally don’t have too much problem with GMO foods. After all, my YEC friend John Sanford created the gene gun through which a large fraction of genetically engineered crops on the planet were made at one time. But one thing that bothers me is genetically engineered bacteria. Church discussed super bacteria created for research applications. I can imagine an accident where germs are created accidentally that become really hard to kill and we basically have an apocalypse. Maybe that will be the fulfillment of prophecy by Jesus, “there will be famines and pestilence”.

Here is the video (with Francis Collins speaking at the start):
https://videocast.nih.gov/summary.asp?Live=21803&bhcp=1

Here is a description of the talk:
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The Christian God and the Problem of Evil

Both Mung and KeithS have asked me to weigh in on the question of whether the existence of evil counts as a good argument against Christianity, as KeithS has maintained in a recent post, so I shall oblige.

It is important to understand that the problem of evil is not an argument against the existence of God or gods, but against what KeithS calls the Christian God (actually, the God of classical theism), Who is supposed to be omniscient, omnipotent and omnibenevolent. KeithS succinctly formulates the problem as follows:

Let’s say I claim that an omniGod named Frank exists — omniscient, omnipotent, and omnibenevolent. Suppose I also claim that Frank regards seahorses as the absolute height of evil. The world contains a lot of seahorses, and Frank, being omnipotent, has the power to wipe them off the face of the earth. Why doesn’t he? Why does he countenance a world full of seahorses?

KeithS emphasizes that it is not enough for the Christian to show that God is on balance benevolent. Rather, the Christian needs to defend the claim that God is omnibenevolent:

The Christian claim is that God is omnibenevolent — as benevolent as it is logically possible to be. Finding that the items on the “good” side of the ledger outweigh those on the “bad” side — if that were the case — would not establish God’s omnibenevolence at all.

Finally, KeithS provides his own take on the problem of evil:

The problem of evil remains as much of a problem as ever for Christians. Yet there are obvious solutions to the problem that fit the evidence and are perfectly reasonable: a) accept that God doesn’t exist, or b) accept that God isn’t omnipotent, or c) accept that God isn’t perfectly benevolent. Despite the availability of these obvious solutions, most Christians will choose to cling to a view of God that has long since been falsified.

He even suggests how he would resolve the problem if he were a theist (emphasis mine – VJT):

Suppose God hates evil and suffering but is too weak to defeat them, at least at the moment. Then any such instances can be explained by God’s weakness.

It addresses the problem of evil without sacrificing theism. I’m amazed that more theists don’t seize on this sort of resolution. They’re too greedy in their theology, too reluctant to give up the omnis.

I think KeithS is onto something here. In fact, I’d like to ditch the conventional Christian views of God’s omniscience, omnipotence and omnibenevolence. It’s time for an overhaul.

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