Tetrapod Evolution and the Evolution of Consciousness

It is here proposed that the evolution of life was destined to produce self consciousness out of physical matter just as surely as self-consciousness is destined to be produced by the build up of matter from the human zygote.

Our external vantage point allows us to see the process whereby an individual human matures from the point of conception  We are in a position to witness all the stages in the life of individual humans. Activities such as birth, death, growth and decay go on all around us. Conversely on the grand scale of things, taking life as a whole, we are in the middle of evolving life and so we don’t have an overall, clear picture of the process.

In this video Sean B. Carroll states that:
…living things are occupying a planet whose surface is always changing. Hurricanes, earthquakes, volcanoes, tectonic movement, ice ages, climate changes whether local or global, all of these keep changing the environments that species are in, they are running to keep up and most of the time they fail. So we have to think about earth’s history to understand life’s history. We have to understand what’s going on at any particular place to appreciate what’s going on with any particular species.

The same could be said for the cells in your body. Their environment is always changing and most of them do not survive as you change from embryo to adult. From an individual cell’s point of view there may not seem to be any direction.Some live some die, some change slowly, others change dramatically. But from the higher perspective of the whole body there certainly is direction.

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Money and happiness

Can money buy happiness?  These people, waiting for hours to buy lottery tickets, seem to think so, or at least are willing to test the hypothesis (turn off your sound — the commentary is annoying):

What does science say?  The short answer is that money can buy happiness, at least up to a point.  The long answer is quite complicated.

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ev

Recent discussions of genetic algorithms here and Dave Thomas’ evisceration of Winston Ewert’s review of several genetic algorithms at The Panda’s Thumb prompted me to dust off my notes and ev implementation.

Introduction

In the spring of 1984, Thomas Schneider submitted his Ph.D thesis demonstrating that the information content of DNA binding sites closely approximates the information required to identify the sites in the genome. In the week between submitting his thesis and defending it, he wrote a software simulation to confirm that the behavior he observed in biological organisms could arise from a subset of known evolutionary mechanisms. Specifically, starting from a completely random population, he used only point mutations and simple fitness-based selection to create the next generation.

The function of ev is to explain and model an observation about natural systems.
— Thomas D. Schneider

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Foundationalism and Anti-Foundationalism

There’s a deep and fascinating question about whether we need “foundations” in our philosophical system, and if so, why and what kind.

First question: is the foundationalism primarily epistemological (foundations of knowledge) or ontological (foundations of being)?*

Second question: insofar as foundationalism implies a hierarchy, is the grounding or fundamental principle at the top of the hierarchy or at the bottom?

These two questions give us four positions:

top-down epistemological foundationalism: rationalism
bottom-up epistemological foundationalism: empiricism
top-down ontological foundationalism: theism/idealism
bottom-up ontological foundationalism: materialism

The ontological foundationalism can be reductive or non-reductive. Hence:
reductive top-down ontological foundationalism: idealism
non-reductive top-down ontological foundationalism: emanationism
reductive bottom-up ontological foundationalism: physicalism
non-reductive bottom-up ontological foundationalism: emergentism

Likewise, anti-foundationalism can also be epistemological or ontological:

epistemological anti-foundationalism: pragmatism (or: the good parts of Hegel/Peirce/Sellars)*
ontological anti-foundationalism: process ontology (or: the good parts of Spinoza/Whitehead/Deleuze)*

The main reason why I have resisted efforts to interpret me as an empiricist or materialist is that both empiricism and materialism are forms of foundationalism. Since I am an anti-foundationalist (both in epistemology and in ontology) I am as opposed to empiricism as I am to rationalism, and as opposed to materialism as I am to theism. My views might look like those of an empiricist/physicalist, but only if one insists on interpreting those views through the lens of the foundationalism that I reject.

As time permits I’ll explore the arguments for epistemological anti-foundationalism and ontological anti-foundationalism. For now I just wanted to get the conversation started.

*I’m leaving aside ethical and political versions of foundationalism and anti-foundationalism, though I think that’s where the philosophical action is really at.

** I’m only citing philosophers in the Western canon here, but Nagarjuna in the Madhyamika tradition of Tibetan Buddhism developed a consistently anti-foundationalist epistemology and ontology one and a half millennia  before it was even conceived of in the West. Within the West, probably Nietzsche and Dewey would be the first consistently anti-foundationalist philosophers.

CRISPR goes retro: Bacteria can also take ‘RNA mug shots’ of threatening RNA-viruses.

The emergence of life for the first time on this planet constitutes the classic question of what came first; the chicken or the egg?!  Did a self-replicating DNA system occur before transcription or translation evolved (the DNA World) or did a self-replicating RNA system first emerge (the RNA world) or did self-replicating protein system first emerge (the Protein World)…or … let’s just leave it there for now. Continue reading

Wright, Fisher, and the Weasel

Richard Dawkins’s computer simulation algorithm explores how long it takes a 28-letter-long phrase to evolve to become the phrase “Methinks it is like a weasel”. The Weasel program has a single example of the phrase which produces a number of offspring, with each letter subject to mutation, where there are 27 possible letters, the 26 letters A-Z and a space. The offspring that is closest to that target replaces the single parent. The purpose of the program is to show that creationist orators who argue that evolutionary biology explains adaptations by “chance” are misleading their audiences. Pure random mutation without any selection would lead to a random sequence of 28-letter phrases. There are 27^{28} possible 28-letter phrases, so it should take about 10^{40} different phrases before we found the target. That is without arranging that the phrase that replaces the parent is the one closest to the target. Once that highly nonrandom condition is imposed, the number of generations to success drops dramatically, from 10^{40} to mere thousands.

Although Dawkins’s Weasel algorithm is a dramatic success at making clear the difference between pure “chance” and selection, it differs from standard evolutionary models. It has only one haploid adult in each generation, and since the offspring that is most fit is always chosen, the strength of selection is in effect infinite. How does this compare to the standard Wright-Fisher model of theoretical population genetics? Continue reading

Hopelessly frustrated – most likely confused regarding latest on Xenoturbella

I would be grateful if somebody could help me out here as Bioinformatics is not my strong card.

Regarding the recent Nature publication

New deep-sea species of Xenoturbella and the position of Xenacoelomorpha

I query the authors’ explanation; to wit…

The sister group relationship between Nephrozoa and

Xenacoelomorpha supported by our phylogenomic analyses implies that the last common ancestor of bilaterians was probably a benthic, ciliated acoelomate worm with a single opening into an epithelial gut, and that excretory organs, coelomic cavities, and nerve cords evolved after xenacoelomorphs separated from the stem lineage of Nephrozoa.

 

My problem arises with their placement of Ctenophora on their own phylogenetic tree as the “more primitive out-group” (for lack of better words on the spur of a rushed moment).  Myself, I always considered Ctenophora as bilateral – in this case more primitively bilateral which IMHO should root the bilateran tree… which of course begs more than one question upon rereading their analysis.

Forget Ctenophores – what about Cnidarians!?  Some taxonomists argue that Cnidarians are descendents of ancient bilateral coelomates and not the other way around. Biologists have known since the 1920s that Cnideria had a directive axis which gave them right and left-hand sides.  Volker Schmidt goes on to argue that non-radially organized hydrozoan larvae have an anterior concentration of sensory and ganglionic nerve elements, suggesting that a fundamental genetic toolkit for the establishment of bilateral and polarized anatomies was already present before the Cnidaria-Bilateria divergence.  Volker Schmidt goes so far as to suggest that diploblastic status of adult Cniderians is derived and that true mesoderm can be even be detected during Cniderian embryogenesis.  OK – I concede that last argument is particularly contentious… but you get my drift.

I am partial to the notion the UrBilateran that subsequently gave rise to “Protostomes” & Deuterostomes and was itself coelomate with possessed a dorsal nerve chord.  Any subsequent acoelomy and pseudocoelomy was derived… ditto ventral nerve chords.  But hey…  now I am being really contentious!

 

 

 

 

Philosophy and Complexity of Rube Goldberg Machines

Michael Behe is best known for coining the phrase Irreducible Complexity, but I think his likening of biological systems to Rube Goldberg machines is a better way to frame the problem of evolving the black boxes and the other extravagances of the biological world.
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A selection-vs-drift version of Weasel

In his endless pursuit of that wascally Weasel, Mung made the following silly claim:

GAs are often used to demonstrate “the power of cumulative selection.” Given small population sizes drift ought to dominate yet in GAs drift does not dominate.

That is clearly false, but for the benefit of Mung (and his cousin Elmer) I have modified my Weasel program to incorporate both drift and selection.  They can now see for themselves that small population sizes are insufficient to guarantee that drift dominates selection.

The code is here. Compile it under Linux using “gcc -std=gnu99 -lm weasel.c -o weasel”.

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The Great Chain of Being: Anthropocentrism

I am reading a book in which the authors set forth the evils of belief in “The Great Chain of Being.”

The Great Chain of Being is, in fact, firmly ingrained in our culture and spirits. It leads to certain grave errors that are commonly acknowledged but difficult for teachers to correct.

The first of these is Anthropocentrism, “the view that man is the measure of all things.”

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Science Friday: A Molecular Biology & Evolution Sampler

My favorite subject-specific journal is Molecular Biology and Evolution (MBE).  This journal publishes on topics primarily related to molecular evolution and evolutionary genomics, which are among my favorite subjects in biology. I’m happy to report that the latest issue of MBE is out today, and there are lots of great articles that I think will be of interest to folks here, many of which are open-access.

I sadly don’t have time to write up any of these articles, but I thought it might be useful to “sample” a few in case any any of you would like to read and discuss them.  Here are a handful that seem particularly interesting:

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Questions for Christians and other theists, part 7: Original Sin and the Fall

Among Christianity’s many odd doctrines is the notion of original sin. The details vary from denomination to denomination, but a common view is that all humans are born into a state of sin because Adam succumbed to temptation in the Garden of Eden, and that this state of sin makes us worthy of God’s eternal condemnation.  Only Christ’s sacrifice can redeem us.

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Structuralist Quackery

Throughout the history of evolutionary biology, as well as many other sciences, there has been a conflict between two styles of thinking. One is conventionally called functionalism, although in evolutionary biology the term “adaptationism” is more frequently used today because a trait’s “functional fit for it’s office” is produced through adaptation by natural selection (i.e., function is explained by adaptation through natural selection). The functionalist stance is one that explains organismal traits through their functional and adaptive values.

The alternative style of thinking does not have a generic name in biology, although in other areas of study it is called “structuralist.”

Michael Denton in Evolution: Still A Theory In Crisis or Gunter P. Wagner in The Intellectual Challenge of Morphological Evolution: A Case for Variational Structuralism?

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Paul Nelson, Evolution, or Design ?

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Paul Nelson, Evolution, or design ? I transcribed it for who is too lazy to see the video, but its worth to watch, a great speech:

Thanks to another reader, I have gotten a copy of McDonald’s actual paper. Reading it, I wonder how many of the Discovery Institute authors have actually read it. How many have just taken what one of their fellows said previously and done what most 10th grade students do for research papers (i.e. change a few words in an attempt to avoid plagiarism).

By adding their own interpretation of the prior authors work (using secondary sources instead of primary sources), quite a bit of error has crept in. I’m sure it’s just a bit of error, we all know that no creationist would say something that wasn’t true, especially if he is quoting an actual scientist’s paper.
No, I can’t do it, that level of sarcasm is too much for me. These people are liars. Either they are directly lying in order to make someone appear to say something that they actually didn’t or they are the worst researchers ever and shouldn’t be allowed to write non-fiction. Which is it creationists?

Spontaneous Generation

A century later we know that the overwhelming obstacle facing spontaneous generation is probability, or rather improbability, resulting from life’s enormously complex phenotypes. If even a single protein, a single specific sequence of amino acids, could not have emerged spontaneously, how much less so could a bacterium like E. coli with millions of proteins and other complex molecules? Modern biochemistry allows us to estimate the odds, and they demolish the spontaneous creation of complex organisms.

Looks like IDists aren’t the only ones to appeal to probability arguments. How does Wagner know what the probabilities are, or that spontaneous generation is even within the realm of what is possible?

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Creationism’s best friend has died

It was not merely Judge John E. Jones who ruled against teaching “intelligent design” (ID), a thinly veiled surrogate for “creation science,” in public schools. The citizens of Dover, Pennsylvania, exercised the power of the ballot to ensure that their city did not appeal Kitzmiller. If the case had reached the Supreme Court of the United States, the justices possibly would have split 5-4 in favor of allowing public schools to teach ID.

Today ID lost its prospect of winning in the Supreme Court: Justice Antonin Scalia, Known For Biting Dissents, Dies At 79. As noted in the Wikipedia article on Edwards v. Aguillard (1987), in which the court nailed shut the coffin of creation science,

Justice Antonin Scalia, joined by Chief Justice William Rehnquist, dissented, accepting the Act’s stated purpose of “protecting academic freedom” as a sincere and legitimate secular purpose. They construed the term “academic freedom” to refer to “students’ freedom from indoctrination”, in this case their freedom “to decide for themselves how life began, based upon a fair and balanced presentation of the scientific evidence”.

Has quite a familiar ring, doesn’t it? The rhetoric of the ID movement was designed by a law professor, Phillip Johnson, to suit a creationism-friendly judge of the Law of the Land. This is indeed a sad day for ID, which already had acquired a moribund pallor.

Darwin Day

Even on his birthday, don’t say Darwin unless you mean it

How Darwin’s name is taken in vain, with mini-reviews of some of the worst offenders

Don’t say Darwin unless you mean it. Above all, don’t say “Darwin” when you mean “evolution”. It’s like saying “Dalton” when you mean atoms. Our understanding of atoms has moved on enormously since Dalton’s time, and our understanding of evolution has moved on similarly since Darwin’s. Neither of them knew, or could have known, the first thing regarding what they were talking about, and both would be delighted at how thoroughly their own work has been superseded. (Dalton of course deserves further discussion in his own right, which I will be providing in a few weeks time.)

DaltonsAtoms

From John Dalton’s A New System of Chemical Philosophy (1808)

Imagine if a lot of people decided that atomic theory was against their religion. We would see a parallel world of sacred science, in which molecules were “intelligently constructed”, and real chemistry would be referred to as Daltonism, or possibly, these days, neo-Daltonism. The scientific dissidents from Daltonism would invoke Dalton’s name on every possible occasion, and draw attention to the many inadequacies of atomic theory as he presented it in 1808.