Lockdown!

Share your experience, tips, advice, questions…

As it seems most communities world-wide are going into voluntary or enforced quarantine that involves staying at home and avoiding physical contact as much as possible, I thought we could have a thread where we could try a bit of mutual support by cheering each other up over the next few days, weeks, months… Who knows?

I don’t know: suggestions on films to watch, books to read, gardening tips, exercise ideas

Usual rules apply plus a guideline. Let’s be kind and supportive to each other.

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267 thoughts on “Lockdown!

  1. My apologies, phoodoo, if I was unclear.
    You asked why anyone would believe that multicellular organisms could mutate fast enough to overcome the rate at which bacteria change. [emphasis added]
    Alan pointed out that no-one would think anything that stupid, and I pointed out why there is no need to believe anything that stupid.
    My response began with an unwritten (but assumed)
    There’s no need to, because multicellular organisms’ responses are not limited to germline mutations.”
    You may not be aware of this, but human beings are generally capable of mounting an effective defense against a novel pathogen in a matter of days; there’s no germline mutation involved. For example,…

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  2. DNA_Jock: You may not be aware of this, but human beings are generally capable of mounting an effective defense against a novel pathogen in a matter of days; there’s no germline mutation involved.

    Right.

    Not evolution.

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  3. phoodoo:
    DNA_Jock,
    I should ignore the fat bacteria hypotheses?

    It was but one of a three-pronged attack on the idea.

    Why should anyone think multi-cellular organisms would have a chance to mutate fast enough to overcome the rate at which bacteria can change?

    What are we to call this mysterious process by which genetic change in bacteria gives them an advantage? 🤔

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  4. phoodoo: Not evolution.

    Two things.
    1) Your original complaint was ‘why hasn’t the earth been overrun by flying flesh-eating bacteria’ and the answer involves predator/prey dynamics and innate and adaptive immunity.
    Which things do evolve, albeit more slowly than RNA viruses evolve.
    2) Some human beings will be unsuccessful in their efforts to mount a defence against a novel pathogen. To the extent that genetic factors (say ACE2 polymorphism) may impact survival rates, then the human population as a whole IS evolving to better resist coronaviruses. That is evolution. See?

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  5. DNA_Jock: Some human beings will be unsuccessful in their efforts to mount a defence against a novel pathogen. To the extent that genetic factors (say ACE2 polymorphism) may impact survival rates, then the human population as a whole IS evolving to better resist coronaviruses. That is evolution. See?

    Cue the predictable “that’s just microevolution but what about BODY PLANS????” in 3 . . . 2. . . 1 . . .

    1+
  6. Kantian Naturalist,

    Well, there’s a slightly smarter response, but let’s see if any of the resident IDists can come up with it. (Hint: if they do, I will mention cancer in response…)

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  7. DNA_Jock: Alan pointed out that no-one would think anything that stupid, and I pointed out why there is no need to believe anything that stupid.

    You made more effort than me to engage with phoodoo. Masochist!

    ETA not literally, of course!!! 😉

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  8. Schizophora:
    Kantian Naturalist,

    I’m still unsure as to what qualifies as a “new body plan.”

    I’m waiting, poised like a coiled spring, ready to pounce if anyone takes that gambit!
    (Ooh I do like mixing my metaphors!)

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  9. I thoroughly recommend the Guardian on-line as a source of news and opinion not under corporate influence. a story I came across:

    https://www.theguardian.com/tv-and-radio/2020/apr/02/how-money-heist-became-netflix-biggest-global-hit

    induced a bit of déjà-vu. I mentioned balcony singing “Bella Ciao” a while back and whiled away a few moments checking various versions on Youtube. I liked this “flashmob” version by the Romanian singer Delia but was puzzled by the red boiler suits and masks. The penny drops.

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  10. Allan Miller: Yep, I dare say graveyards are littered with people immune to the possibility of viral evolution, if not the virus itself.

    “Viral evolution” is when the mama virus has sex with the papa virus and oops, hocus-pocus “descent with modification” something something.

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  11. Alan Fox,

    I tend to go to the Guardian, but by Christ they paint a gloomy picture! You think I’m bad! 😃

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  12. Nonlin.org: “Viral evolution” is when the mama virus has sex with the papa virus and oops, hocus-pocus “descent with modification” something something.

    Oh yeah, hilarious strawman, it’s just like that. Perhaps you’d like to join phoodoo in the search for a name for the mysterious process by which a genetic change in a pathogen enhances its net ability to spread.

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  13. Allan Miller: Perhaps you’d like to join phoodoo in the search for a name for the mysterious process by which a genetic change in a pathogen enhances its net ability to spread.

    “Process”?!? I hear that “process” not only “enhances”, but also “diminishes”. Also brings you a cold beer and turns on the TV. Is there anything that “process” doesn’t do? Oh yeah. Making any sense is what it’s not doing.

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  14. Nonlin.org: “Process”?!? I hear that “process” not only “enhances”, but also “diminishes”.

    Indeed. If one variant is increasing in frequency, it is inevitable that another is decreasing, since frequencies must add up to 100%. This is not controversial, surely?

    Also brings you a cold beer and turns on the TV. Is there anything that “process” doesn’t do? Oh yeah. Making any sense is what it’s not doing.

    A career in comedy beckons.

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  15. Nonlin.org: “Viral evolution” is when the mama virus has sex with the papa virus and oops, hocus-pocus “descent with modification” something something.

    You should see what Benzer, Brenner and Barnett were able to do with virus sex. That’s how they figured out the genetic code was a triplet code…

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