The Skeptics Wink and Nod.

Here is an informative little video by a guy named Steve Mould who does a lot of “science” videos on youtube.  Its all (ostensibly) about how simple little processes can make “meaningful” structures from stochastic processes-and he uses magnetic shaped little parts to show this.  Its a popular channeled followed by millions, and is often referenced by other famous people in the science community-and his fans love it.

And hey, it does show how meaningful structures CAN form from random processes.  Right?  So you can learn from this.  Wink, wink.  Nod, nod. And all the skeptics will know exactly what he is really saying.  Cause we are all part of the clique that knows this language-the language of the skeptic propagandist.  I mean, he almost hides it, the real message, it is just under the surface, and the less skeptically aware, the casualist, might even miss it.  The casualist might not learn as much about Steve Mould and what he is trying to say here-but the skeptic knows.  “See, atheism is true! Spread the word!” Steve has given the wink. The same wink used by DeGrasse Tyson, and Sean Carroll, Lawrence Krauss, Brian Greene, and on and on.  You know the one.

And for 95% of his viewers, whether they know it or not, they got his message.  I mean, look, its plain as day, right?  He just showed you, that is certainly a meaningful structure that arose from random processes, isn’t it?  Its defintely meaningful, its a, a, a , well, it’s shape that, we have a, a  name for…that’s kind of…anyway, defintely random, I mean other than the magnets and the precut shapes, and the little ball with nothing else inside, and the shaking only until its just right then stopping kind of way…That’s random kind of right???

But there are 5% percent of his viewers that spotted his little wink and nod, and said, hold on a second.  If you want us to believe that your little explanation about how simply life can form from nonsense without a plan, how blind exactly do you want us to be?  95%, they are hooked, you got them (Ryan StallardThere are so many creationist videos this obliterates. Especially 4:18.). But some likeGhryst VanGhod helpfully point out: “this is incorrect. the kinesin travels along fibres within the cell and takes the various molecules exactly where they need to be, they are not randomly “jumbling around in solution”. https://youtu.be/gbycQf1TbM0  ” and then you get to see a video that tells you just a few more of the things that are ACTUALLY happening which are even more amazing if you weren’t already skeptical (the real kind).

And if you go through some more of the comments you will notice a few more (real) skeptics, not the wink and nod kind, and you will start to notice why the wink nod propogandist skeptics everywhere you look in modern culture are a very puposefully designed cancer on knowledge and thought.

1,212 thoughts on “The Skeptics Wink and Nod.

  1. phoodoo: It doesn’t matter what God one believes in, without random dust, your God is the same as mine.

    That’s what I thought you were saying. Any god is better than no god.

    Well, I disagree. I’m fine with wondering,. not knowing, and enjoying the life I have without any expectation of eternity. I doubt you’ve read any of Pullman’s novels so you may not appreciate how your use of the word “dust” suggests a more appealing idea than an eternal heaven of individual souls praising the lord.

  2. Alan Fox,

    You are the one talking about what one wants Alan, I am talking about what is. Your theory has holes, and even the biologists are starting to acknowledge it. Without your random dust, (as bad as I know you want it, its already blowing away), the only thing left is a creator-whether you like it or not.

    But it does make more sense why you can’t see it-as you have said, you don’t want to.

  3. phoodoo: …the only thing left is a creator-whether you like it or not.

    What is is unaffected by either of our likes or dislikes. I am not attracted to any religious explanation or belief system that I’ve come across so far. If you find some religion a benefit or a comfort to you, good for you.

    I’m still curious which religion you find suits you and whether you recommend it to others. What about Michael Flynn and his one religion? Does that appeal?

  4. OMagain:
    The fact we’re looking at the end product of millions of years of evolution seems to escape many. Relatively inefficient processes are replaced by relatively less inefficient processes as they are stumbled upon, or not.

    Human designers strive for simplicity and re-usability. Demeters principle suggests disconnected systems should have minimal knowledge of each others inner workings.

    None of which we observe in biology. We observe massive cross talk in systems. Stochastic behavior. Pulling on one thread changes 100 other things. And yet people point at biology and “see” human style design.

    Those people have never created anything complex is my take away from that. Or they’d look at biology and see it as designed by anything unlike they have encountered before. Iterative processes that use absurd “shortcuts” that may be crippling in the long term.

    On the contrary, nature has vastly superior technology to what we have. The fact that as you say ‘pulling one thread changes 100 other things’ shows the complexity and high level of design, not millions of years of bump and run, jury rigged solutions. That is the skeptic’s fall back storyline.

    Any human design we have ever discovered has already been deployed by nature. There are literally tons more awesome design concepts waiting to be unveiled. Unfortunately, as long as we have design deniers in the lab, we won’t get anywhere.

    for the record, today’s scientists have absolutely no idea what they are observing. If they did, they would be designing awesome AI by now.

  5. Steve

    Don’t disagree we have much to learn about the world around us. What is stopping you or anyone from finding out?

  6. Alan Fox: I see Steve stated his position around eight years ago.

    I support a front loading position.I support the original definition of evolution as ‘an unfolding of pre-existing rudiments’.I support the notion that life is succumbing to the effects of the environment and is degrading from an original optimum design; in contrast to the darwinian evolutionary take that the genome is a mess as a result of unguided processes.


    I think we can predict that some time in the future we should be able to detect something like quantum templates that act as command and control of the development of lifeforms. In fact, if im not mistaken we are going in the direction of understanding light as instrumental in genomic activity.so it wont be all that long before we make the jump to the intelligent properties of light.

    Do you still think this?

    http://theskepticalzone.com/wp/is-evolution-of-proteins-impossible/comment-page-3/#comment-19464

    absolutely. it is in line with my current comments where I stated that information is embedded in nature.

    Look, it simple. If we really understood what we were looking at, we would have imitated nature’s design capability by now and have created some awesome AI. we haven’t done so because IMO we are stuck in this randomness, chaotic, unrelated, uncoordinated, morass of thinking. denying design in nature is pretty stupid. We know that nature has already deployed all the design concepts we ‘invented’. So what else can nature teach us? a shitload

    Skepticism is the science’ fentanyl.

  7. Steve: We know that nature has already deployed all the design concepts we ‘invented’. So what else can nature teach us? a shitload

    Why not start a company then and show everyone how it’s done?

    Afraid to put your money where your mouth is perhaps?

    Not confident in your claims perhaps?

    Wanting other people to do all the work perhaps?

  8. phoodoo:
    Darwinists have always had this problem and they know it. If you don’t have unguided, random nothingness doing the creating, then your no designer desires go flying out the window.

    It seems like phoodoo thinks that “Darwinism” equals all of science, the explanation for everything for an atheist, or something like that. Oh, but it has to consists of random nothingness too. I never read any book by Darwin claiming that random nothingness did everything. The books seem about observations of life and its evolution, nothing about anything else, and never about random nothingness “creating” everything. Who the hell knows what books phoodoo read.

    phoodoo:
    Of course you all can’t accept that, so the only other option is denial ~ and that denial is in the form of, well, it’s not God, just Nature! Nature strives! But nature isn’t a God, oh no no, it’s, it’s, hey, hey, I can’t hear you, na , na.

    Well, I don’t know about anyone else. I cannot talk for anybody other than me. I don’t say “it’s not God”, I say that all we can observe is what’s around us. We call that nature. it has some way of working. It has deterministic phenomena, which are as far from being random nothingness as can be, and we have some underlying seemingly random phenomena, like quantum fluctuations, for example, which are not “nothingness.” Therefore, it seems like nature works by a combination of random and deterministic phenomena. I can put together those kinds of ingredients and see patterns forming, some very interesting. These things combine around me. I can observe that, and patterns do emerge by themselves, without my help. More importantly, as far as we can observe, without anybody else’s help. So, if I observe nature doing amazing things around me, who am I to deny that nature can do it?

    Then we have some nut-jobs who come and talk to me about incoherent magical beings in the sky. They want me to accept that if I have no answers to something I must consider their incoherent fantasies, and that leaving those fantasies in the category where they belong is some kind of denial. Sorry, but, I need something better than incoherent blabber to start talking about the possibility that some magical beings did anything at all. Mischaracterization of science, or of Darwinian hypotheses and theories, as “random nothingness”, doesn’t help, won’t help.

  9. phoodoo to Alan Fox,
    The fatal flaws of evolution have nothing to do with what you like or don’t like.

    You cannot know if evolution has any flaws, let alone fatal ones. You think that evolution means “random nothingness.”

  10. phoodoo: Every former Darwinist has the same fear as you. Without random mutations, your hope of no God goes crumbling into your meaningless dust. Sorry for that.

    This doesn’t really make sense to me. Whether or not God exists has nothing to do with whether or not there’s evidence of design in nature.

    Even if there were evidence of design in nature, it wouldn’t show that God exists. It wouldn’t even make it more likely that anything like God exists.

    And whether there’s evidence of design in nature is separate from whether there’s self-organizing systems, trends towards increased complexity, or whether or not “mutations” (whatever you mean by that!) are “random” (whatever you mean by that!)

    Also, not that it matters, but I’m not an atheist. I don’t like discussing my religious beliefs with strangers, so I’d rather not talk about it here.

  11. OMagain:
    CharlieM: Coordinated activity throughout is a necessity.

    OMagain: What happens to cells where coordinated activity was less coordinated then others?

    Like any aspect of living systems there is always conflict between integral processes and disruptive external influences. For example DNA repair involves coordinated activity and much else besides. Lymphocytes make use of DNA repair processes to deal with antigens. So there is much more going on within cells than pure coordinated activity

    OMagain: Why is it that we don’t appear to see cells now that don’t lack such “coordinated activity”? Can you think of any reason?

    From the very beginning any cell that has ever existed has needed some sort of coordinated activity within its membranes.

  12. Alan Fox:
    CharlieM: And the availability of these tRNAs depends on them being suitably charged by enzyme activity.

    Alan Fox: Aminoacyl tRNA synthetases may interest you. Might be a better avenue to argue divine intervention. You wouldn’t be the first.

    Yes, these are the enzymes I was thinking about. But why mention divine intervention? We can appreciate the wisdom and orchestrated processes within the living systems themselves without having to invoke any external interventions.

  13. Alan Fox:
    CharlieM: You ignore the fact that there are a multitude of enzymes which have the task of speeding up reactions.

    Alan Fox: Oh, no, no, no. How they speed up reactions which happen without them but at much lower rates is fascinating. They are, to use a bad analogy, like marriage brokers.

    Think about all the proteins that need to be enclosed within “barrel” structures to allow them to fold correctly. Do you think that they would be produced in enough numbers (if at all) to carry out their function if they were just left to float about freely in the cytoplasm?

  14. OMagain:
    CharlieM: There are many examples of molecules being enclosed or confined to designated spaces.

    OMagain: Sigh. “designated spaces”. How did that come about then? Who designated what?

    Designated by more subtle field activity similar to the way the material is laid down as shown in this well known video Of in a similar way in which iron filings take up a pattern designated by the lines of force.

    Mitosis is a very much more intricate process than splitting a cell down the middle. The daughter cells are usually partitioned like the mother cell.

  15. Kantian Naturalist: This doesn’t really make sense to me. Whether or not God exists has nothing to do with whether or not there’s evidence of design in nature.

    Even if there were evidence of design in nature, it wouldn’t show that God exists. It wouldn’t even make it more likely that anything like God exists.

    And whether there’s evidence of design in nature is separate from whether there’s self-organizing systems, trends towards increased complexity, or whether or not “mutations” (whatever you mean by that!) are “random” (whatever you mean by that!)

    Also, not that it matters, but I’m not an atheist. I don’t like discussing my religious beliefs with strangers, so I’d rather not talk about it here.

    Ok, so you don’t know what random mutations are. Cool, me either. So we both agree the ‘scientific consensus” of biology is cobblygook.

    But here’s where we differ-if what we see in life is that biological systems self-assemble, if they have a logical method of construction, if they display a teleological intelligence, then to say but that doesn’t imply anything else whatsoever about an intelligent force behind that is really just complete denial. To have a philosophical stance of saying OK, I see that life systems know what they are doing. They have purpose, they have intent, AND it evens goes so far as to create beings who are conscious of that intelligence, BUT, BUT, that’s where my philosophy ends. I am just going to chalk that up to , whatever. Not interested in the how or why. Just is. Voila.

    That in my opinion is the mindset of a 15 year old skateboarding, fortnight playing slacker. And even worse still, you have the audacity to call the idea of intelligent design bullshit. You think a belief of “nature just does it, beats me” is rational. But intelligent design, oh, what bullshit! If that is what studying philosophy is, maybe playing fortnight all day is a better use of one’s time.

    I wish that would have been the argument in Kitzmiller vs. Dover. “Well judge, we can all agree that life definitely has an intelligent method of coming into being, but that doesn’t mean we should be able to teach children that! The ONLY thing children should be taught in schools about how life came into being is random mutations and natural selection, and, mumble mumble, some other things like that…”

    What is life all about? How did we get here? “Um, like nature just does man. Bang, bang, awesome!”

    I suggest your criticism of the Discovery Institute is misplaced.

  16. Neil Rickert: In this thread, phoodoo is the one who is exhibiting intense fear.

    So what say you Neil, is KN crazy? I mean he believes the scientific consensus of the last 100 years is nonsense! There is no such thing as random mutations. Who even knows what hat means?? No, life is teleological. It has a plan. Some might even use the term, a design (Wait, who said that, who said that? Stone him!).

    Are you with Jock, and Rummy, and Alan, and the “scientific consensus” of settled science crowd? Is Goodwin a crank? Is Stuart Kaufman a crank? Random mutations, natural selection, rah, rah, rah until the end of time?

  17. CharlieM: But why mention divine intervention?

    Because, were I to play ID’s devil’s advocate, Aminoacyl tRNA synthetases would be my candidate for an example of “Intelligent Design”. I’m sure some ID proponent with better advocacy skills than the odious Upright Biped could have got more notice using aars as an example.

  18. It’s getting a mite (more) incoherent.

    Without random mutations, your hope of no God goes crumbling into your meaningless dust

    so WITH random mutations, the atheists are all set, apparently?
    Or is he trying sarcasm again?
    phoodoo seems to have a knee-jerk reaction to things he doesn’t understand: splutter and fume, and yell “That can’t be right!”
    It is not just limited to subjects that impinge on his unconventional religious beliefs: mathematics is problematic too. He quite determinedly refuses to learn anything, happy to be outraged by this “War of Christmas” paranoia.
    So, because phoodoo does not understand what phoodoo means by random mutations[??], then the scientific consensus must be wrong. That’s his claim.
    I think a key insight is the discovery that he does much of his research on social media, in particular YouTube. I found his citing of YouTube comments as evidence of err, the unGodliness of mankind, I guess … to be particularly revealing.
    KN and I have both tried to point out to him that the videos YouTube suggests for him is driven by his past history of interacting with such videos, but to no avail — he still writes

    After Kn suggested Scishow, and I looked at some of their videos, my youtube feed automatically also suggested a similar channel, called Forrest Valkai. One of the first videos it suggested for me, Ask An Atheist Day. Because what else would you expect from a science channel?

    KN notes ” I’ve been watching SciShow for a few years and I’ve never heard of Forrest Valkai.”
    but phoodoo resolutely misses the point and responds

    First, it was your suggestion that lead directly to more scientists talking about atheism. They go hand and hand.

    He really has no clue as to how the online environment he experiences has been colored by his own peccadilloes.
    As Kathryn noted:

    I’ve never met a fundamentalist creationist who actually understood how evolution works. They embarrass themselves.

    Oh, the unGodly people commenting on YouTube!

  19. phoodoo: I wish that would have been the argument in Kitzmiller vs. Dover. “Well judge, we can all agree that life definitely has an intelligent method of coming into being, but that doesn’t mean we should be able to teach children that! The ONLY thing children should be taught in schools about how life came into being is random mutations and natural selection, and, mumble mumble, some other things like that…”

    How how carefully phrased!

    I can happily agree that life can indeed be Intelligently Designed. We’re not too far off doing such ourselves. Nobody disputes that.

    The question is, is there evidence that the origin of life on planet earth was Intelligent Design.

    We can all agree that no, there is no such evidence.

    So, what precisely is it that you want to teach children about “life definitely has an intelligent method of coming into being”? Do you actually know?

    Odd how you did not write: Well Judge, we can all agree that the evidence that life was designed is clear.

    Even you know that’s a bridge too far.

    So, what exactly is it that you want to teach children phoodoo?

  20. phoodoo: What is life all about?

    Prison camps and misery. Right? But for the right people.

    The people in that picture are terrorists, according to phoodoo.

  21. phoodoo: Are you with Jock, and Rummy, and Alan, and the “scientific consensus” of settled science crowd? Is Goodwin a crank? Is Stuart Kaufman a crank? Random mutations, natural selection, rah, rah, rah until the end of time?

    At least they have something to say and have said it. People know who they are and can evaluate their arguments on their merits whereas you’ve never actually made an argument for something at all.

    You seem jealous, frankly, of the people you name.

  22. DNA_Jock,

    Are you talking to me or KN? Because he has no idea what mutations are, little yet random mutations. And apparently thinks you are a fool for believing that evolution nonsense.

  23. phoodoo: And apparently thinks you are a fool for believing that evolution nonsense.

    Divide and rule is it? You don’t rise to the level of sophistication to make that work I’m afraid. Everybody here in the reality based community is united in one thing – phoodoo does not understand evolution.

  24. phoodoo: Because he has no idea what mutations are, little yet random mutations.

    Little yet random mutations? Is that something that you’ve discovered in your basement all on your widdle-own is it?

  25. phoodoo:
    DNA_Jock,
    Are you talking to me or KN?

    I was writing for everybody except you and KN… that’s why I referred to you both in the third person.

    Because he has no idea what mutations are, little yet random mutations.

    Wrong. He has a good understanding of what random mutations are. He is unclear as to what YOU mean by those terms, viz:

    whether or not “mutations” (whatever you mean by that!) are “random” (whatever you mean by that!)

    to which you replied

    Ok, so you don’t know what random mutations are. Cool, me either. So we both agree the ‘scientific consensus” of biology is cobblygook.

    Which I made fun of:

    So, because phoodoo does not understand what phoodoo means by random mutations[??], then the scientific consensus must be wrong. That’s his claim.
    [emphasis in original]

    I also tried to explain to you that Alphabet Inc. makes money by feeding you YouTube videos that upset you.

    And apparently thinks you are a fool for believing that evolution nonsense.

    Not the vibe I’m getting from him at all. He did note that I was committed to fallibilism; perhaps you misunderstood.
    I’ve never met a fundamentalist creationist who actually understood how evolution works. They embarrass themselves.

  26. phoodoo: Ok, so you don’t know what random mutations are. Cool, me either. So we both agree the ‘scientific consensus” of biology is cobblygook.

    On the issue about what mutations are, and whether they are random. I’m currently reading Lenny Moss’s What Genes Can’t Do. He argues that the whole conceptual framework in which biologists talk about genes is a muddle. And if that’s a muddle, then so too is the conceptual framework about what mutations are.

    As for “random”: this word is also overused, and very little careful thought goes into what it really means. Of course in one sense it means the following: that there is no empirically detectable process that can anticipate what traits will be adaptive in the future and then cause those traits to appear.

    But here’s where we differ-if what we see in life is that biological systems self-assemble, if they have a logical method of construction, if they display a teleological intelligence, then to say but that doesn’t imply anything else whatsoever about an intelligent force behind that is really just complete denial. To have a philosophical stance of saying OK, I see that life systems know what they are doing. They have purpose, they have intent, AND it evens goes so far as to create beings who are conscious of that intelligence, BUT, BUT, that’s where my philosophy ends. I am just going to chalk that up to , whatever. Not interested in the how or why. Just is. Voila.

    Yes, we do disagree here. And here’s why.

    Firstly, I think you make the inference from teleology to design far too quickly. This can be seen by asking, “is design the same thing as teleology or is design the explanation for teleology?”

    (This debate is not new with us. It was already the central issue in the 18th century debate between preformationists and epigeneticists in German embryology.)

    Kant suggests, in his “Critique of Teleological Judgment” in Critique of the Power of Judgment that there’s a distinction between extrinsic teleology and intrinsic teleology. Intrinsic teleology is the purposiveness or goal-oriented character of each and every individual organism. Extrinsic teleology is the plan or design which causes organisms to come into existence and pass out of existence.

    So with that Kantian distinction in mind, we can see that it requires an inference to get from intrinsic teleology to extrinsic teleology. The mere fact of accepting the former doesn’t mean that the latter gets to come along for free.

    So my main disagreement with intelligent design is that it ignores Kant’s distinction between two very different concepts of teleology. At Uncommon Descent we see occasional promotion of J. Scott Turner and Steve Talbott, who are certainly quite eloquent and forceful advocates of intrinsic teleology. Yet neither of them accepts intelligent design, precisely because because they are sophisticated enough to know that intrinsic teleology is neither identical with extrinsic teleology, nor does intrinsic teleology logically entail extrinsic teleology.

    Second, we disagree about how to carve up the boundary between philosophy and science.

    I certainly accept that the question, “why does the universe have fundamental physical structure — the laws of physics and the constants of fundamental physics — that enables the emergence of purposive organisms, including intelligent, conscious, and rational animals?” is a question worth asking.

    But I do not think that this question can have a scientific answer. Even if it does have a rational answer, it can’t be a scientific answer. We cannot take any measurements that aren’t made somewhere in this Universe, which means that we cannot confirm or disconfirm any claims about the origins of the Universe.

    This is then my other big criticism of intelligent design: that it is promoted as a scientific explanation, when I don’t see how it could be.

  27. DNA_Jock:
    CharlieM: Most intracellular processes go on in spite of and not because of activities which they have to contend with such as Brownian motion.

    DNA_Jock: Nope. Utterly wrong. By way of illustration, you wrote:

    “CharlieM: Without this activity, if tRNAs and their matching amino acids relied on just bumping into each other without the presence of these enzymes then the occasions when they came together would be vastly reduced.”

    DNA_Jock: How the heck do you think those enzymes work? They rely on just bumping into the right aa and the right tRNA.

    I was exaggerating there. This is a common tactic in arguments about life. Those who argue for blind evolution like to exaggerate any haphazard chaotic processes and us who see evolution as more directed tend to exaggerate any well organized purposeful processes.

    The fact is that the chemical properties of matter is ideal for producing living systems and these systems make use of a wide range of physical forces. And the more that is being revealed about living systems the fewer examples there are of accidental chance events being prominent. As Behe loves to point out what was once thought of as a bag of amorphous jello now reveals immense complexity. Haphazard chaos as a generative force is going the same way as the “God of the gaps”.

    DNA_Jock: Also a gem:

    CharlieM [to Alan]: You ignore the fact that there are a multitude of enzymes which have the task of speeding up reactions.

    DNA_Jock: Actually, that’s the only thing that enzymes do. Evah. I suspect that you are making a fairly common mistake, imbuing enzymes with some magical property. They are catalysts.
    I encourage you to take an introduction to biochemistry course at a reputable university. Then, perhaps, you will understand what the literature tells you about “the behavior of tRNA”.

    Enzymes working within a process must work together in systems in which the timing and rate of reactions are critical to its overall function. The rates of reactions are interdependent. If one essential reaction was left to proceed without its associated enzyme, even if in theory the reaction could take place without the enzyme, it most probably would not get the opportunity to do so because it would be too far out of sync with the rest of the system.

    I’ve been looking at how the amount of amino acids in cells are determined and I found this article on arginine:

    Arginine: beyond protein, Sidney M Morris, Jr published in, “The American Journal of Clinical Nutrition”> It states:

    …arginine imported from outside the cell appears to be the preferred substrate for NO synthesis by endothelial cells [a phenomenon known as the arginine paradox], but endogenously synthesized arginine may be more important for high-output NO synthesis by activated smooth muscle cells. Further complicating the picture is recent evidence that multiple intracellular arginine pools exist in endothelial cells but not in some other cell types.

    (Simplified diagram of arginine reactions from link shown below)

    Is it too simplistic to say that amino acids just float around in the cytoplasm? They have a constant turnover which takes a great deal of regulation.

    One other finding about ribosomes that I found interesting:

    Newly identified process of gene regulation challenges accepted science

    Ribosomes, which make proteins, are startlingly variable in their composition and associations. This variability confers on them the ability to regulate genes, confounding previous ideas, Stanford researchers say…

    “This discovery was completely unexpected,” said Maria Barna, PhD, assistant professor of developmental biology and of genetics. “These findings will likely change the dogma for how the genetic code is translated. Until now, each of the 1 to10 million ribosomes within a cell has been thought to be identical and interchangeable. Now we’re uncovering a new layer of control to gene expression that will have broad implications for basic science and human disease.”

    Yet another complex level of control.

    CharlieM: Coordinated activity throughout is a necessity.

    DNA_Jock: Well, if you mean ‘coordinated’ in the sense of “When temperature increases, there is a coordinated increase in the rate of all these reactions”, then suuuure, I guess.

    No. Coordination is far more sophisticated than your basic example. For instance, take an essential amino acid and think about its journey though your body and the various routes it can take.

    If you are seeking to imply that {there must have been | there must be} a coordinator, then support your assertion, for once

    The coordinator is the organism through which all the processes take place.

  28. phoodoo: Are you talking to me or KN? Because he has no idea what mutations are, little yet random mutations. And apparently thinks you are a fool for believing that evolution nonsense.

    I don’t think anyone is a fool for accepting the Modern Synthesis. I just think there are serious problems with it.

  29. Kantian Naturalist: This is then my other big criticism of intelligent design: that it is promoted as a scientific explanation, when I don’t see how it could be.

    Only a few comments ago phoodoo was making the case that children should be taught the truth about design and the the origin of life. The question as to what actually would be taught remains unadressed however.

    People like phoodoo can demonstrate that intelligent design is in fact a scientific explanation by giving the explanation that they presumably must have in order to believe it should be taught in schools.

    Or do you just want to skip over that step phoodoo?

  30. CharlieM:
    From the very beginning any cell that has ever existed has needed some sort of coordinated activity within its membranes.

    Isn’t this kind of the definition of a cell? Ever since planets existed they have been large masses orbiting around some stars. Like that?

  31. Kantian Naturalist: I don’t think anyone is a fool for accepting the Modern Synthesis. I just think there are serious problems with it.

    I suspect that phoodoo has trouble understanding that Darwin’s hypotheses are pretty much a tiny seed compared to what’s going on today in terms of evolutionary theory. So, I wouldn’t go as far as imagining that phoodoo knows what the modern synthesis is.

    By the way, I’ve got that and the newer synthesis books as a gift from a very good friend. The modern synthesis is not as dumb as Gould wanted to portray it, and the “newer” not as illuminating as pretentiously presented by their authors. The modern synthesis is much more modest in acknowledging potential pitfalls, and being very careful about where things were pointing out. Anyway, phoodoo seems to think science is literalist and dogmatic, holding to ideas that cannot be better defined or refined, like “random mutations”, for fear of being excommunicated.

    I have tried to explain more precise terminology and how science works, but it doesn’t seem to register. To phoodoo it’s either “random dust” or magical beings in the sky. The mere idea that things could work on their own seems opposite to what science investigates. Apparently, we’re not looking for equations to describe patterns, we’re only producing equations for rolling dice. Imagine that. The laws of newton being rolling dice algorithms, rather than describing the way gravitation seems to behave. But that doesn’t register. If gravitation has a precise, or a series of precise, deterministic-looking equation(s), then that’s some magical being in the sky, not nature.

  32. Rumraket:
    CharlieM: And the availability of these tRNAs depends on them being suitably charged by enzyme activity. Without this activity, if tRNAs and their matching amino acids relied on just bumping into each other without the presence of these enzymes then the occasions when they came together would be vastly reduced.

    Rumraket: Rolling a die once per week or forty times per minute, it’s going to be “stochastic” what it lands on either way.

    Yes the uncatalyzed rate of the aminoacylation of tRNA is very low. The rate of the reaction has nothing to do with it being stochastic or not.

    CharlieM: Now that would be what I would call stochastic.

    Rumraket: That makes you have a highly idiosyncratic, and frankly nonsensical, definition of ‘stochastic’. Stochasticity of chemical reactions is not related to their rate of occurrence over unit time, but to the number of different possible outcomes and the probabilistic nature of how they occur.

    Why? We are in agreement that the bonding of amino acids to tRNAs has a stochastic element. Is it stochastic that they attach in a set order? Also from here

    Synthetases charge the amino acids with high-energy chemical bonds that speed the later formation of new peptide (protein) bonds. Synthetases also have powerful editing capabilities; if the wrong amino acid is added to a tRNA, the enzyme quickly dissolves the bond.

    Does that sound like a stochastic process?

  33. CharlieM: Does that sound like a stochastic process?

    If you go back in time will it remain the same process, or will it change?

    How far can you go back in time without it changing?

    When it starts to change, if it does, how is it changing?

    If we continue to go back in time to the “first” version of the process what will that look like?

    In the step previous to the first step, what does that look like?

  34. Just as phoodoo gets a hopelessly distorted view of the world, courtesy of Alphabet Inc., so does Charlie with his reliance on scientific press releases.
    His “ribosomes are hetergeneous” story is messier, and a lot less ground-breaking, than his source (a Stanford Press Release) makes out, and his Science Daily blurb from Urbana-Champaign refers to “high energy bonds”, which makes me scream.
    Nice to see Charlie continue with the bald assertions of top-down coordination and ongoing whataboutism, though. He’s making my point for me.

  35. CharlieM: Why?

    I already explained that. You spoke about the rate(speed) of the reaction, not the degree of bias in the distribution of outcomes of the reaction. You insinuated that the uncatalyzed reaction being slower made it more stochastic, but it’s rate is irrelevant to whether it is stochastic or not. Hence my dice analogy.

    CharlieM:
    We are in agreement that the bonding of amino acids to tRNAs has a stochastic element.

    Good. That’s really all I wanted to say about that.

    CharlieM:
    Is it stochastic that they attach in a set order?

    There is a stochastic element to that too, yes. But the distributions are much more biased. No biochemical process known has a 100% fidelity. Even with editing domains, tRNA-synthetases still occasionally do mistranslate.

    Even better, occasional mistranslations are known under some conditions to facilitate evolution:
    Mistranslation can promote the exploration of alternative evolutionary trajectories in enzyme evolution.

    There are even organisms known with aminactyl-tRNA-synthetases that lack editing domains. Somehow these still manage to make a successful living despite higher rates of mistranslation. Someone wrote an entire PhD thesis about that.

  36. OMagain: If we continue to go back in time to the “first” version of the process what will that look like?

    Interestingly, the pre-LUCA last common ancestor of certain aminoacyl-tRNA-synthetase enzymes have been phylogenetically reconstructed, and they are highly promiscuous catalysts. They will accept basically all amino acids, with only slight preferences for their specific descendant substrates(class I synthetases are biased towards preferring class I substrantes, and class II enzymes prefer class II substrates). That basically shows that the specific extant enzymes evolved from less discriminating ancestors at earlier stages in the evolution of the genetic code and translation system.

    See figure 6C in this paper.

  37. Kantian Naturalist: I don’t think anyone is a fool for accepting the Modern Synthesis. I just think there are serious problems with it.

    Kn, Jock says you know what random mutations are. So what makes you think I was referring to something different than what you call random mutations? Or is Jock wrong again?

    Do you think Jock believes life is teleological? Or are you going to claim you also don’t know what that means? Or Jock doesn’t know what that means? Or all those people writing books that you recommend don’t know what that means?

  38. Entropy,

    Nature and culture “are understood to be one continous and unified creative process, not two domains that are distinguished by unique human attributes.” (12) The concept of meaning belongs also to nature, in a “biological hermeneutics”. The great enigma is “who” creates, and Goodwin emphasizes that it is not a “builder” in the form of a separate entity in a cell (105 f) but instead the process itself on the basis of a “morphogenetic field” in the form of “the pattern of relationships that exist in a developing organism at different levels of organization” (127). In this way the enigma of self-organization seems to be solved: at every level there is a “head” for the organization, from the beginning the fertilized egg, and then different combinations of cells, that this gives rise to. At the same time as there in the universe seems to be a creative power that forces it all. – Goodwin

    How did life start? Is the evolution of life describable by any physics-like laws? Stuart Kauffman’s latest book offers an explanation-beyond what the laws of physics can explain-of the progression from a complex chemical environment to molecular reproduction, metabolism and to early protocells, and further evolution to what we recognize as life. Among the estimated one hundred billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of “becoming” in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.

    Building on concepts from his work as a complex systems researcher at the Santa Fe Institute, Kauffman focuses in particular on the idea of cells constructing themselves and introduces concepts such as “constraint closure.” Living systems are defined by the concept of “organization” which has not been focused on in enough in previous works. Cells are autopoetic systems that build themselves: they literally construct their own constraints on the release of energy into a few degrees of freedom that constitutes the very thermodynamic work by which they build their own self creating constraints. Living cells are “machines” that construct and assemble their own working parts. The emergence of such systems-the origin of life problem-was probably a spontaneous phase transition to self-reproduction in complex enough prebiotic systems.

    Is this what you are calling the modern synthesis? That living cells are machines that construct their own parts?

    Do you believe physics alone can not explain where we came from?

    The modern synthesis is founded in morphogenetic fields? Are you a closet Rupert Sheldrake fan?

  39. morphogenetic field ≠ morphic resonance.

    “I’ve never met a fundamentalist creationist who actually understood how evolution works. They embarrass themselves.”

  40. DNA_Jock: All your ‘exquisite coordination’ is an artefact of your muddled thinking, no more.

    KN thinks you are nuts.

    A professor, biologist, and physiologist argues that modern Darwinism’s materialist and mechanistic biases have led to a scientific dead end, unable to define what life is—and only an openness to the qualities of “purpose and desire” will move the field forward.

    Scott Turner contends. “To be scientists, we force ourselves into a Hobson’s choice on the matter: accept intentionality and purposefulness as real attributes of life, which disqualifies you as a scientist; or become a scientist and dismiss life’s distinctive quality from your thinking. I have come to believe that this choice actually stands in the way of our having a fully coherent theory of life.”

    Growing research shows that life’s most distinctive quality, shared by all living things, is purpose and desire: maintain homeostasis to sustain life. In Purpose and Desire, Turner draws on the work of Claude Bernard, a contemporary of Darwin revered among physiologists as the founder of experimental medicine, to build on Bernard’s “dangerous idea” of vitalism, which seeks to identify what makes “life” a unique phenomenon of nature. To further its quest to achieve a fuller understanding of life, Turner argues, science must move beyond strictly accepted measures that consider only the mechanics of nature.

    When are you going to move beyond the strictly accepted measures that consider only the mechanics of nature Jock? Tomorrow?

  41. DNA_Jock:
    morphogenetic field ≠ morphic resonance.

    “I’ve never met a fundamentalist creationist who actually understood how evolution works. They embarrass themselves.”

    Morphogenetic Fields of Body and Mind

    Presenter: Dr. Rupert Sheldrake
    According to the hypothesis of formative causation, all self-organizing systems, including crystals, plants and animals contain an inherent memory, given by a process called morphic resonance from previous similar systems. All human beings draw upon a collective human memory, and in turn contribute to it. Even individual memory depends on morphic resonance rather than on physical memory traces stored within the brain. This hypothesis is testable experimentally, and implies that the so-called laws of nature are more like habits.

    Morphic resonance works through morphic fields

    I have never met a mathematician who understands how words work.

    Idiot.

Leave a Reply